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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Small extracellular vesicles from dental follicle stem cells provide biochemical cues for periodontal tissue regeneration

Fig. 2

DFSCs-sEVs promoted proliferation and migration of PDLSCs. (A) Experiment design for proliferation and migration assays. (B, C) The effect of DFSCs-sEVs on PDLSCs proliferation detected using EdU assay, and quantification of EdU positive cells. Scale bar = 100 μm. (D) CCK-8 assay detected the effect of DFSCs-sEVs on PDLSCs proliferation. (E) Cell cycle assay showed DFSCs-sEVs enhanced the proportion of S phase and G2 phase of PDLSCs. (F) Wound healing assay detected the effect of DFSCs-sEVs on PDLSCs migration. Scale bar = 100 μm. (G) Quantitative analysis of migration rates. n = 3, *p < 0.05; **p < 0.01; ***p < 0.001; #p < 0.0001

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