Fig. 1

Effect of DES treatment on mice testes. DES exposure led to wide range of abnormal changes. Vehicle-treated control testes were soft and oval shaped (j, k). In few mice, testes were atrophied (b) and in others they were bigger in size (a, d, e) red in colored (g, h) and very hard to touch (d–f, m). At places, epididymis was tightly adhered to testis (g, h). Epididymis was reddish (i) and completely different from control (l). Aged DES-exposed mice testes also had pathology (n, o)