Table 2 Outcomes and quality evaluation of the included studies
References | Sample size | Number of AEs | AEs | Endpoint* | Risk of bias-NOS | |
|---|---|---|---|---|---|---|
Injection site skin reactions | Other | |||||
Almadori [22] | 62 | 1 | Skin infection (1) | None | â‘ â‘¡ | 6 |
Blezien [23] | 7 | NA | Lip oedema and pain | None | â‘¡ | 8 |
Francesco [24] | 6 | NA | None | None | Skin changes | 7 |
12 | 2 | Transient paresthesia of finger (2) | None | ①③④⑤ | 8 | |
Keyszer [25] | 3 | 3 | None | Minor respiratory tract infection (3) | â‘¢ | 7 |
Park [26] | 18 | 4 | Transient pale fingers (3) | Dizziness after local anesthesia (1) | ①③④⑤⑥ | 7 |
Scuderi [27] | 6 | NA | None | None | Skin changes | 5 |
Wang [28] | 5 | 0 | None | None | ③⑥ | 8 |
Zhang [29] | 14 | 6 | None | Minor respiratory tract infection (5)/diarrhea (1) | ③⑦ | 8 |