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Table 3 Comparison of the VAS scores before and after treatment in the SVF and the control group

From: Mid-term prognosis of the stromal vascular fraction for knee osteoarthritis: a minimum 5-year follow-up study

Before or after treatment

Group

Pre-treatment

1 year

2 years

3 years

5 years

Sum

F

p value

SVF

3.96 ± 1.46

1.69 ± 1.63***

2.04 ± 1.78***

2.43 ± 1.66***

2.86 ± 1.83**

2.60 ± 1.84

75.990

 < 0.001

HA

3.55 ± 0.91

3.42 ± 0.99ns

3.50 ± 1.39ns

3.73 ± 1.29ns

3.95 ± 1.23ns

3.63 ± 1.18

9.067

 < 0.001

Sum

3.73 ± 1.19

2.65 ± 1.57

2.85 ± 1.73

3.16 ± 1.60

3.47 ± 1.61

3.17 ± 1.59a

64.378a

 < 0.001a

F

2.414

42.441

30.065

23.921

16.751

18.030a

(F = 49.319

p value < 0.001)b

p value

0.121

 < 0.001

 < 0.001

 < 0.001

 < 0.001

 < 0.001a

  1. SVF, stromal vascular fraction; HA, hyaluronic acid
  2. aF statistic and p value of main effect
  3. bF statistic and p value of crossover effect
  4. *p value < 0.05; **p value < 0.01; ***p value < 0.001; ns, non-significant (p value > 0.05), compared with pre-treatment