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Table 2 Patient laboratory findings

From: Safety and long-term improvement of mesenchymal stromal cell infusion in critically COVID-19 patients: a randomized clinical trial

Laboratory tests

 

UC-MSC (n = 11)

Placebo (n = 6)

p value

Blood count

Total lymphocyte (µL)

737 ± 299.55

1652.33 ± 2032.80

0.01

 

Leukocytes (µL)

10,959.73 ± 4591.77

9605 ± 3998.52

n.s

 

Neutrophils (µL)

9899.73 ± 4354.47

8266 ± 3671.02

n.s

 

Hemoglobin (µL)

13.35 ± 1.69

12.68 ± 2.56

n.s

 

Hematocrit (%)

41 ± 5

38 ± 7

n.s

 

Platelets (µL)

271,690.91 ± 75,889.73

296,500 ± 54,013.89

n.s

Serologic

D-Dimer (mg/L)

7.75 ± 10.81

6.45 ± 4.83

n.s

 

C-Reactive protein (mg/dL)

38 ± 81

9 ± 5

n.s

 

Ferritin (ng/mL)

2760.53 ± 3167.67

1600.38 ± 1258.86

n.s

 

Troponin I (pg/mL)

218 ± 655

132 ± 209

n.s

Biochemical

Creatinin (mg/dL)

2.07 ± 1.71

1.92 ± 1.84

n.s

 

ALT (µ/L)

49 ± 40

29 ± 14

n.s

 

AST (µ/L)

60 ± 33

45 ± 19

n.s

 

Total Bilirubin (mg/dL)

0.84 ± 1.41

0.33 ± 0.12

n.s

 

Direct bilirubin (mg/dL)

0.59 ± 1.17

0.18 ± 0.06

n.s

 

Indirect bilirubin (mg/dL)

0.24 ± 0.28

0.15 ± 0.10

n.s

Main lymphocytes subgroups

TCD3

242.17 ± 176.44

471.90 ± 205.33

0.02

 

TCD4

195.120 ± 94.84

346.06 ± 194.50

0.01

 

TCD8

105.83 ± 85.91

107.06 ± 41.42

n.s

 

B

90.47 ± 53.31

143.56 ± 146.16

n.s

 

NK

56.54 ± 35.54

41.92 ± 27.21

n.s

 

Treg

11.26 ± 6.20

21.57 ± 6.66

n.s

 

Plasmablasts

17.04 ± 17.01

14.94 ± 7.88

n.s

  1. ALT, alanine aminotransferase; AST, aspartate aminotransferase; NK, natural killer; n.s, not significant; Treg, CD4 regulatory T lymphocytes; UC-MSC, umbilical cord mesenchymal stromal cell