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Table 2 Efficacy outcomes of WBFPS, PFWT, TcPO2, ABI and TBI over time

From: The peripheral blood mononuclear cells versus purified CD34+ cells transplantation in patients with angiitis-induced critical limb ischemia trial: 5-year outcomes and return to work analysis—a randomized single-blinded non-inferiority trial

  Group Baseline P value 1 year P value 3 years P value 5 years P value
WBFPS PBMNCs 7.60 ± 1.53 0.503 1.08 ± 2.26 0.116 0.79 ± 2.55 0.508 0.78 ± 2.86 0.730
  PCCs 7.28 ± 1.81   2.13 ± 2.38   1.30 ± 2.85   1.04 ± 2.42  
PFWT, seconds PBMNCs 323.7 ± 383.8 0.898 976.1 ± 385.1 0.365 992.7 ± 488.4 0.894 998.2 ± 398.6 0.956
  PCCs 308.8 ± 430.3   870.6 ± 429.8   1010.0 ± 417.4   1004.6 ± 410.3  
TcPO2, mmHg PBMNCs 21.3 ± 12.4 0.851 28.5 ± 20.7 0.487 29.0 ± 21.2 0.095 29.6 ± 20.2 0.142
  PCCs 20.6 ± 13.7   24.6 ± 18.6   20.2 ± 14.8   22.4 ± 13.2  
ABI PBMNCs 0.554 ± 0.222 0.230 0.692 ± 0.261 0.147 0.617 ± 0.210 0.575 0.723 ± 0.200 0.631
  PCCs 0.472 ± 0.254   0.586 ± 0.247   0.657 ± 0.285   0.692 ± 0.250  
TBI PBMNCs 0.174 ± 0.191 0.252 0.321 ± 0.132 0.085 0.420 ± 0.308 0.407 0.438 ± 0.224 0.836
  PCCs 0.117 ± 0.155   0.268 ± 0.073   0.354 ± 0.246   0.422 ± 0.312  
  1. The data are presented as mean ± SD
  2. WBFPS, Wong–Baker Faces Pain Rating Scales; PFWT, pain-free walking time; TcPO2, transcutaneous oxygen pressure; ABI, ankle-brachial index; TBI, toe-brachial index; PBMNC, peripheral blood mononuclear cell; PCC, purified CD34+ cell; SD, standard deviation