Passage (P) | Total studies | ASC results | BMSC results | Overall |
---|---|---|---|---|
(a) Comparison: HPL 10% vs FBS 10% | ||||
P1 | 4 studies ASC: 1 study, not useful data, BMSC: 3 studies with useful data | No useful data | 74 participants MD − 0.90 favor to HPL 10%, IC 95% − 2.35, − 0.55 I2 = 97% | 74 participants MD − 0.90 favor to HPL 10%, IC 95% − 2.35, − 0.55 I2 = 97% |
P2 | 5 studies ASC: 2 study, 1 with useful data; BMSC: 3 studies with useful data | 30 participants MD − 4.58 favor to HPL 10%, IC 95% − 7.15, − 2.01 I2 = not applicable | 74 participants MD − 2.76 favor to HPL 10%, IC 95% − 3.81, − 1.71 I2 = 88% | 104 participants MD − 2.97 favor to HPL 10%, IC 95% − 3.97, − 1.97 I2 = 79% |
P3 | 5 studies ASC: 2 study, 1 with useful data; BMSC: 3 studies, 2 with useful data | 30 participants MD − 7.45 favor to HPL 10%, IC 95% − 10.17, − 4.73 I2 = not applicable | 74 participants MD − 4.68 favor to HPL 10%, IC 95% − 6.05, − 3.31 I2 = 85% | 104 participants MD − 5.17 favor to HPL 10%, IC 95% − 6.62, − 3.72 I2 = 81% |
P4 | 4 studies ASC: 2 study, 1 with useful data; BMSC: 2 studies, 1 with useful data | 30 participants MD − 9.66 favor to HPL 10%, IC 95% − 12.38, − 6.94 I2 = not applicable | 36 participants MD − 7.16 favor to HPL 10%, IC 95% − 8.11, − 6.21 I2 = not applicable | 66 participants MD − 8.07 favor to HPL 10%, IC 95% − 10.43, − 5.71 I2 = 65% |
P5 | 3 studies ASC: 1 study with useful data; BMSC: 2 studies, 1 with useful data | 14 participants MD − 14.00 favor to HPL 10%, IC 95% − 16.47, − 11.53 I2 = not applicable | 36 participants MD − 10.29 favor to HPL 10%, IC 95% − 11.75, − 8.83 I2 = not applicable | 50 participants MD − 12.01 favor to HPL 10%, IC 95% − 15.63, − 8.38 I2 = 84% |
P7 | 3 studies ASC: 1 study with useful data; BMSC: 2 studies with useful data | 10 participants MD − 21.00 favor to HPL 10%, IC 95% − 25.96, − 16.04 I2 = not applicable | 36 participants MD − 9.63 favor to HPL 10%, IC 95% − 17.21, − 2.04 I2 = 98% | 46 participants MD − 13.10 favor to HPL 10%, IC 95% − 20.48, − 5.73 I2 = 97% |
(b) Comparison: HPL 5% vs FBS 10% | ||||
P1 | BMSC: 1 study | No useful data | 24 participants MD − 0.39 favor to HPL 5%, IC 95% − 0.51, − 0.27 I2 = not applicable | No pooled analyses available |
P2 | 2 studies ASC: 1 study with no useful data; BMSC: 1 studies with useful data | No useful data | 24 participants MD − 0.89 favor to HPL 5%, IC 95% − 1.07, − 0.71 I2 = not applicable | No pooled analyses available |
P3 | 3 studies ASC: 1 study with no useful data; BMSC: 2 studies with useful data | No useful data | 42 participants MD − 1.73 favor to HPL 5%, IC 95% − 3.34, − 0.11 I2 = 83% | No pooled analyses available |