Fig. 2
From: Potential effect of amniotic fluid-derived stem cells on hyperoxia-induced pulmonary alveolar injury
Confocal Microscopic images of lung tissue (A–C). DIC image (A). Labelled AF-MSCs (red fluorescence) homed on alveolar wall (B). Merged DIC and fluorescent images (C) scale bar 25 mm. Representative graphs of mean values of TV, MRV, RR, FVC and FEV1/FVC% respectively (D–H). a; significant compared to CG. b: significant compared to HG. c: significant compared to CFM-TG. d: significant compared to SC-PG. e: significant compared to SC-TG. Pairwise comparison bet. Each 2 groups using Post Hoc Test (Tukey). Significance at p ≤ 0.05. Error bars represent S.E.M. n = 10 in all groups. (I) Representative tracings of airway flow (upper) and tidal volume (lower) in each panel of the different studied groups. Air flow and tidal volume were decreased in HG, CFM-TG, Unt -G. Treatment with stem cells improved both parameters in SC-PG and to a lesser extent in SC-TG. Abbreviations: DIC; differential interference contrast. CG; control group, HG; Hyperoxia group, CFM-TG; Cell-free media-treated group, SC-PG; Stem cells-prophylactic group, SC-TG; Stem cells-treated group, Unt-G Untreated group, TV; tidal volume, MRV; minute respiratory volume, RR; respiratory rate, FVC; forced vital capacity, FEV1; forced expiratory volume 1