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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Breast carcinoma-amplified sequence 2 regulates adult neurogenesis via β-catenin

Fig. 6

Intracranial injection of AAV-DJ8-targeted cells. A Diagram of AAV intracranial injection strategy. Abbreviations as in Fig. 4. WT mice at age 8 weeks were injected with AAV-DJ8-GFP and killed 2 weeks after injection. B Representative images of AAV-DJ8-GFP-targeted cells. The cells in hippocampal dentate gyrus include stem cells (Sox2), immature neurons (DCX), astrocytes (GFAP) and interneurons (GAD67). The 40-μm vibratome coronal brain sections of mice underwent IFA staining. Arrows: indicated cells. Scale bar: 100 μm. C Proportion of GFP+Sox2+, GFP+DCX+, GFP+GFAP+ cells (in SGZ or not in SGZ) and GFP+GAD67+ to total GFP+ cells in dentate gyrus: 3 sections per mouse from 3 individual mice. D The pie chart of AAV-DJ8-GFP-targeted cells. Data are mean ± SEM by Student’s t test

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