Skip to main content
Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Epiregulin increases stemness-associated genes expression and promotes chemoresistance of non-small cell lung cancer via ERK signaling

Fig. 3

Inhibition of ErbB receptor reversed resistance of NSCLC. The cell viability of A549-TR cells (A) and H1299 cells (B) treated with 1 µM afatinib combined with 100 ng/mL taxol for 48 h, n = 3. C, D The representative images (C) and the statistics data (D) of A549-TR spheres treated with 1 µM afatinib combined with 100 ng/mL taxol, n = 3. E, F The representative images (E) and the statistics data (F) of H1299 spheres treated with 1 µM afatinib combined with 100 ng/mL taxol, n = 3. (G) RT-qPCR detection for the stemness-associated genes in A549-TR cells treated with 1 µM afatinib, n = 3. (H) RT-qPCR detection for EMT-related genes in A549-TR cells treated with 1 µM afatinib for 48 h, n = 3. Scale bars, 100 μm in black; TR, taxol resistance; *, p < 0.01; **, p < 0.01

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512