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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Adipose-derived stromal cells increase the formation of collagens through paracrine and juxtacrine mechanisms in a fibroblast co-culture model utilizing macromolecular crowding

Fig. 1

Results from custom RT2 PCR Profiler Arrays, depicting volcano plots of differentially regulated genes between the different experimental groups. Cells were harvested at day 10. A NHDF + TGF-β vs NHDF. B Juxtacrine + TGF-β vs NHDF + TGF-β. C Juxtacrine + TGF-β vs NHDF Paracrine + TGF-β. D ASC Paracrine + TGF-β vs NHDF Paracrine + TGF-β. Based on experiments with three ASC donors (paracrine co-cultures, juxtacrine co-cultures, and ASC monocultures), with one replicate per ASC donor, and three replicates for NHDF monocultures with or without TGF-β. Significance level: *p < 0.05

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