Table 3 Chemical factors from stem cells on MAPK/ERK signaling pathway
Chemical factors | Cell source | Function (MAPK/ERK) | References |
|---|---|---|---|
ERBB4 | Mesenchymal stem cells | Inhibition | [48] |
Spred1 | Neural stem cells | Inhibition | [49] |
miR-125b | Mesenchymal stem cells | Inhibition | [50] |
HOTAIRM1-1 | Mesenchymal stem cells | Inhibition | [50] |
miR-133a | Mesenchymal stem cells | Inhibition | [51] |
HIF-2α | Mesenchymal stem cells | Activation | [52] |
IGF-1 | Mesenchymal stem cells | Activation | [53] |
TGF-β3 | Mesenchymal stem cells | Activation | [53] |
bFGF | Neural stem cells | Activation | [54] |
VEGF | Multi-potent progenitor cells | Activation | [55] |
BDNF | Mesenchymal stem cells | Activation | [56] |
METTL1 | Embryonic stem cells | Activation | [57] |
FGF8 | Spermatogonial stem cells | Activation | [58] |
IGF-1 | Neural stem cells | Activation | [59] |
SCGF-beta | Mesenchymal stem cells | Activation | [60] |
HGF | Mesenchymal stem cells | Activation | [60] |
MCP-1 | Mesenchymal stem cells | Activation | [60] |
miR-126 | Mesenchymal stem cells | Activation | [61] |
SMSCs-126-Exos | Mesenchymal stem cells | Activation | [62] |
ApoE | Neural stem cells | Activation | [63] |
IL-8 | Mesenchymal stem cells | Activation | [64] |
IL-6 | Mesenchymal stem cells | Activation | [65] |