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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Modeling of mitochondrial bioenergetics and autophagy impairment in MELAS-mutant iPSC-derived retinal pigment epithelial cells

Fig. 3

Autophagy and mitophagy signaling in control and p0 cells. Control and p0 ARPE-19 cells were treated with or without bafilomycin 100 nM for 3 h. Cell lysates were analyzed by Western Blotting using indicated antibodies. Cropped representative blots from n = 2 experiments. Quantification of A pYSTAT3/total-STAT3 ratio. B p-AMPKα/total-AMPKα ratio. C LC3-II/actin ratio. D ApoE/actin ratio. E PGC-1α/actin ratio. F PINK1/actin ratio. G p62/actin ratio. Full-length gels are presented in Additional file 1

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Stem Cell Research & Therapy

ISSN: 1757-6512