Table 1 The possible suppressors for SARS-CoV-2 infection

Camostat mesylate

TMPRSS2 suppressor, the effect on S proteins

Treatment of chronic pancreatitis, postoperative reflux esophagitis, and SARS-CoV

[5, 92]

Olumiant (Baricitinib)

JAK suppressor, the effect on S proteins

Treatment of rheumatoid arthritis

[93]

rhACE2 (APN01)

Decrease in proteolytic binding peptide angiotensin II

SARS-CoV infections, cardiovascular disease

[5, 94]

Umifenovir (Arbidol/ARB)

Preventing HA protein-interceded membrane fusion

influenza infection

[95]

T-705 (Favipiravir)

Inhibiting RdRp

influenza viruses, WNV, yellow fever virus, FMDV

[96, 97]

Abacavir (Ziagen)

RTIs (reverse-transcriptase inhibitors)

Treatment of HIV

[98]

Roflumilast (Daxas/Daliresp)

Preventing PDE4

COPD

[98]

Almitrine mesylate

is a respiratory stimulant

COPD

[98]

Chloroquine phosphate

IFN-α pathway

antimalarial

[99, 100]

Remdesivir

RdRp inhibitor

Treatment of Ebola and Marburg infections

[101]

Convalescent plasma

viral-specific antibodies

Ebola virus, H1N1, SARS-CoV-1, MERS-CoV

[102]