Table 1 General characteristics of 202 included trials
Characteristics | Number/value | Percentage (%) |
|---|---|---|
Submit year | ||
Prior to 2003 | 6 | 3.0 |
2003–2007 | 18 | 8.9 |
2008–2012 | 45 | 22.3 |
2013–2017 | 60 | 29.7 |
2018-mid-2021 | 73 | 36.1 |
Study period | ||
L ≤ 36 m | 71 | 35.2 |
36 < L ≤ 72 m | 32 | 15.8 |
72 m < L | 18 | 8.9 |
NA | 81 | 40.1 |
Actual/estimated enrollment | ||
n < 50 | 144 | 71.3 |
50 ≤ n < 100 | 30 | 14.9 |
100 ≤ n < 200 | 13 | 6.4 |
n ≥ 200 | 11 | 5.5 |
NA | 4 | 2.0 |
Location | ||
Single center | 133 | 65.8 |
Single country-multicenter | 39 | 19.3 |
Multicountry-multicenter | 16 | 7.9 |
NA | 14 | 6.9 |
Recruitment status | ||
Completed | 69 | 34.2 |
Recruiting | 45 | 22.3 |
Active, not recruiting | 18 | 8.9 |
Not yet recruiting | 10 | 5.0 |
Terminated | 8 | 4.0 |
Withdrawn | 8 | 4.0 |
Suspended | 11 | 5.5 |
Unknown | 33 | 16.3 |
Participant gender | ||
Male and female | 189 | 93.6 |
Male only | 13 | 6.4 |
DMC | Â | Â |
No | 45 | 22.3 |
Yes | 117 | 57.9 |
NA | 40 | 19.8 |
Publication (including results)* | ||
Primary completion and publication (including results) | 39 | 19.3 |
Primary completion but not publication (including results) | 73 | 36.1 |
Uncompletion | 90 | 44.6 |