Skip to main content

Table 1 General characteristics of 202 included trials

From: Clinical trials of stem cell-based therapies for pediatric diseases: a comprehensive analysis of trials registered on ClinicalTrials.gov and the ICTRP portal site

Characteristics Number/value Percentage (%)
Submit year
Prior to 2003 6 3.0
2003–2007 18 8.9
2008–2012 45 22.3
2013–2017 60 29.7
2018-mid-2021 73 36.1
Study period
L ≤ 36 m 71 35.2
36 < L ≤ 72 m 32 15.8
72 m < L 18 8.9
NA 81 40.1
Actual/estimated enrollment
n < 50 144 71.3
50 ≤ n < 100 30 14.9
100 ≤ n < 200 13 6.4
n ≥ 200 11 5.5
NA 4 2.0
Location
Single center 133 65.8
Single country-multicenter 39 19.3
Multicountry-multicenter 16 7.9
NA 14 6.9
Recruitment status
Completed 69 34.2
Recruiting 45 22.3
Active, not recruiting 18 8.9
Not yet recruiting 10 5.0
Terminated 8 4.0
Withdrawn 8 4.0
Suspended 11 5.5
Unknown 33 16.3
Participant gender
Male and female 189 93.6
Male only 13 6.4
DMC   
No 45 22.3
Yes 117 57.9
NA 40 19.8
Publication (including results)*
Primary completion and publication (including results) 39 19.3
Primary completion but not publication (including results) 73 36.1
Uncompletion 90 44.6
  1.  * May 2020 as the deadline. NA, not available