Fig. 5
![Fig. 5](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13287-022-02988-9/MediaObjects/13287_2022_2988_Fig5_HTML.png)
4-key-genes are poor prognostic predictors for ICC patients with adjuvant TACE. A The transcriptional levels of 4-key-genes were evaluated via qRT-PCR in 40 paired ICC specimens. B Kaplan–Meier curve suggested that ICC patients with adjuvant TACE tend to have poor overall survival if they had a high transcriptional level of the 4-key-genes. C Representative western blot analysis of ICC tumor tissues and paired paratumor tissues. D The 4-key-genes expression in TMA (71 ICC patients with adjuvant TACE). E Representative immunohistochemical images of 4-key-genes expression in TMA (magnification, 200 ×). (**p < 0.01, ***p < 0.001; T, tumor; P, paratumor)