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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Exosomal miR-132-3p from mesenchymal stromal cells improves synaptic dysfunction and cognitive decline in vascular dementia

Fig. 7

EXmiR-132-3p infusion reduces cortical and hippocampal Tau hyperphosphorylation in VD mice. A, C The Tau hyperphosphorylation in cortex was detected by immunofluorescence staining (p-Tau, red; MAP-2, green). Scale bar, 40 μm. B, D The Tau hyperphosphorylation in hippocampus was detected by immunofluorescence staining (p-Tau, red; MAP-2, green). Scale bar, 40 μm. Data represent the mean ± SEM. n = 20 fields from 3 mice per group. Three independent experiments were performed. *p < 0.05

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