Fig. 9
EXmiR-132-3p incubation decreasing neuron apoptosis and tau phosphorylation by activating Ras/Akt/GSK-3β signaling pathway in OGD-treated neurons. A, B Representative images and summary data showing the level of Ras and phosphorylation of Akt and GSK-3β in OGD-treated neurons after various MSC EX incubation. C The neuron apoptosis was detected by flow cytometry. D, E Representative images and summary data showing the p-Tau level in OGD-treated neurons after various MSC EX incubation (p-Tau, green; nucleus, blue). Scale bar, 40 μm. F The phosphorylation of Tau in OGD-treated neurons after various MSC EX incubation was measured by western blotting. Data represent the mean ± SEM. Three independent experiments were performed. *p < 0.05