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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: miR-126-3p-loaded small extracellular vesicles secreted by urine-derived stem cells released from a phototriggered imine crosslink hydrogel could enhance vaginal epithelization after vaginoplasty

Fig. 7

miR-126-3p silencing attenuated the effect of hUSC-sEVs on VK2 cells. A Representative images of the scratch migration assay of VK2 cells. Scale bar: 100 µm. B Quantitative analysis of the migration behavior of VK2 cells. n = 3 per group. C VK2 cells were treated with miR-126-3p inhibitor or control inhibitor for 36 h, and the expression of filaggrin and CK10 was measured by qPCR. n = 3 per group. D The protein levels of Spred1, ERK1/2, p-ERK1/2, PIK3R2, AKT and p-AKT were analyzed by western blotting. E Densitometric quantification of the relative band intensity in D. n = 3 per group. *P < 0.05, **P < 0.01, ***P < 0.001

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Stem Cell Research & Therapy

ISSN: 1757-6512