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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: RA signaling pathway combined with Wnt signaling pathway regulates human-induced pluripotent stem cells (hiPSCs) differentiation to sinus node-like cells

Fig. 6

The biological mechanism by which RA promotes pacing cell differentiation. a–e The mRNA level of the pacemaker markers on D20. f The mRNA level of TBX5 on D0–D19. g–h The protein expression of TBX5. Data points present as means ± SEM (n = 5). *p < 0.05 compared to CHIR = 0 group. #p < 0.05 compared to CHIR = 3 group. &p < 0.005 compared to RA + CHIR = 0 group

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Stem Cell Research & Therapy

ISSN: 1757-6512