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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Mesenchymal stem cells derived from adipose accelerate the progression of colon cancer by inducing a MT-CAFs phenotype via TRPC3/NF-KB axis

Fig. 4

TRPC3 expressed on the MT-MSCs regulates the invasion and migration of colon cancer cells in vitro. A The expression of IL6 and IL8 following knockdown of TRPC3 in MT-CAFs and HCT116 cells at different days. B, C The expression of IL6 and IL8 were detected by ELISA. D Transwell migration assays were conducted to evaluate the invasion capacity of HCT116 cells. E Quantitative results (P < 0.05). F The migration ability of HCT116 cells was detected using a wound healing assay

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Stem Cell Research & Therapy

ISSN: 1757-6512