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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Mesenchymal stem cells derived from adipose accelerate the progression of colon cancer by inducing a MT-CAFs phenotype via TRPC3/NF-KB axis

Fig. 7

TRPC3 expressed on the MT-CAFs contributes to the growth and progression of colorectal cancer xenografts in vivo. A/B Representative photographs of HCT116 tumors generated in the three different groups. C Quantitative analysis of the results shown in figure B (P < 0.05). D/E The expression of proliferation factor ki67 in tumor tissues of different groups was assessed by IHC, figure E shows the quantitative data (P < 0.05). F/G Macrophage infiltration into tumor tissues was detected by staining for CD206 using immunohistochemistry. Representative images of CD206 staining for each group are shown (magnification × 200). H The number of lung metastases was examined by HE staining. I Quantitative analysis of the results shown in figure H (P < 0.05)

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Stem Cell Research & Therapy

ISSN: 1757-6512