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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Cyst stem cell lineage eIF5 non-autonomously prevents testicular germ cell tumor formation via eIF1A/eIF2γ-mediated pre-initiation complex

Fig. 4

Reduction in eIF5 increased cell apoptosis. A TUNEL staining at the apex of control and Tj > eIF5 RNAi testes. B The number of TUNEL-positive cells at the apex of testes. Control, n = 14; Tj > eIF5 RNAi, n = 15. C Relative mRNA level of eIF5 in S2 cells treated with NC, siRNA-1086, siRNA-1356, and siRNA-1539. D TUNEL staining in S2 cells treated with NC and siRNA-1086. E The percentage of TUNEL-positive cells in S2 cells. NC, n = 10; siRNA-1086, n = 9. F CCK-8 assay for S2 cells transfected with NC and siRNA-1086. n = 3 per group. DNA was stained with Hoechst (blue). (**P < 0.01; ***P < 0.001. Scale bars: 50 µm)

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Stem Cell Research & Therapy

ISSN: 1757-6512