Fig. 3From: Bone marrow mesenchymal stromal cells for diabetes therapy: touch, fuse, and fix?MSCs and β-cells and fusion to β-MSCs. β-MSC transdifferentiation after fusion may initially result in immature polyhormonal cells and later process to the expression of mature β-cell markers. Epigenetic modifiers and transcription factors are major contributors to this process inside the shared cytoplasm. Further differentiation may be achieved after transplantationBack to article page