Fig. 6

Expression of miR-148-5p and Notch signaling pathway in liver tissues of patients with fibrosis. a The expression levels of miR-148-5p were examined in normal and fibrosis liver tissues. b Western blot analysis showing the expression of Notch2 in normal and fibrosis liver tissues. Protein samples in different lanes were obtained from different individuals. c Histological analysis was performed by sirius red staining (Scale bars, 500 µm), and immunohistochemical analysis of normal and fibrosis liver tissues for the expression of Notch2 and Hes1 (Scale bars, 100 µm). d Collagen proportion (stained red) of sirius red staining, and quantification of Notch2 and Hes1-positive areas in normal and fibrosis liver tissues