Fig. 2

Tracing of ADSC-derived exosomes in vivo and in vitro. A DiR-labeled ADSC-derived exosomes injected into mouse tail veins. B, C Fluorescence imaging results of mice and dissected aortas (B), and statistical analysis (C). D–E Representative fluorescence image of tissues from the DiR-labeled exosomes-treated group on day 3 (D), and statistical analysis (E). F The PKH67-labeled exosomes were incubated with macrophages. G–H The PKH67 labeled ADSC-exos taken up by the macrophages were examined under the fluorescence microscope (G), and statistical analysis (H). Scale bar: 25 μm. Repetition = 3. A one-way ANOVA was performed to compare data between groups. *P value < 0.05, **P value < 0.01, ***P value < 0.001