Fig. 6

Histology and immunohistochemistry of an explanted cell-bearing kidney from a diabetic transplanted animal. A Hematoxylin and eosin staining showing transplanted cells under the renal capsule. B Insulin-positive cells (green). C C-peptide-positive cells (red). D Coexpression of insulin and c-peptide within the same cells (yellow). E Glucagon-positive cells (red) were in a different cell population than insulin-positive cells. F Somatostatin-positive cells (red) were in a different cell population than insulin-positive cells. Control staining of a kidney explanted from a normal control. G Negative for insulin. H Negative for c-peptide