Fig. 2

ADSC-EXO treatment ameliorates hepatic function in DEN/CCl₄-induced liver fibrosis mice. A Schematic diagram of DEN/CCl₄-induced liver fibrosis and ADSC-EXO treatments strategy in mice. B Liver/body weight ratio of vehicle (PBS), control (DEN/CCl₄) and ADSC-EXO (DEN/CCl₄ + ADSC-EXO) mice (n = 5/group). C Representative images of liver gross. D H&E staining of liver morphology in each group mice (scale bar, 50 μm). E Sirius Red staining of collagen deposition (scale bar, 100 μm) in each group mice. F Ishak score statistical of each group mice. G Quantitative statistics of Sirius Red staining by Image J software analysis. H Hepatic function serology markers AST and ALT level of mice serum at mice killed timepoint. All data are shown as the mean ± SEM, *p < 0.05, **p < 0.01 comparing with corresponding controls by unpaired t test between two groups