Fig. 4

Hair follicle reconstruction ability of Pelage DPCs and Whisker DPCs. DPCs were fixed with neonatal mice epidermal cells and were injected into nude mice to test hair follicle reconstruction ability. Complete hair follicle can be seen after 4 weeks injection by Whisker DPCs induced (A, F, white arrow indicated reconstructed hair follicle). Pelage DPCs can also reconstruct complete structure hair follicle as the Whisker DPCs did (B, G, white arrow indicated reconstructed hair follicle). As the control, neonatal epidermal cells alone failed to reconstruct hair follicle (C, H), and also, both DPCs alone failed to reconstruct hair follicle (D, E, I, J). Average HFs of Whisker and Pelage DPCs induced hair follicle reconstruction showed no significant difference under the same amount of injected cells. Both DPCs possessed the ability to reconstruct hair follicle with complete structure