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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: ETV2 promotes osteogenic differentiation of human dental pulp stem cells through the ERK/MAPK and PI3K-Akt signaling pathways

Fig. 4

RNA‐Seq analysis of hDPSCs after osteogenic induction for 10 days. a Heatmap of 1121 differentially expressed genes in hDPSCs transfected by ETV2-encoding lentivirus, with or without Dox treatment. b, c Bubble plots showing GO (b) and KEGG pathway (c) enrichment analysis of the differentially expressed genes. d qRT–PCR validation of 3 upregulated genes and 3 downregulated genes in RNA‐Seq results. e Results of western blot analysis showed that ETV2 overexpression increased the level of phosphorylated ERK and AKT in hDPSCs. Error bars, mean ± SD (n = 3).* P < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512