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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: ETV2 promotes osteogenic differentiation of human dental pulp stem cells through the ERK/MAPK and PI3K-Akt signaling pathways

Fig. 6

ETV2 overexpression enhanced the osteogenic potential of hDPSCs in vivo. a Schematics of the experimental process. b Micro-CT scanning of rat calvarial defects (n = 6). Upper panel: Representative images of Micro-CT scanning at 8 weeks post-surgery; Lower panel: Quantitative analysis of BMD, BV/TV, and Tb.Th. c-e Quantitative analysis of newly formed bone upon HE staining of the rat calvarial defect model (c), and HE (d) and Masson (e) staining in mice model. Error bars, mean ± SD. * P < 0.05

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