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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Melatonin enhances autologous adipose-derived stem cells to improve mouse ovarian function in relation to the SIRT6/NF-κB pathway

Fig. 7

Effects of ADSCs and 5 μM MLT-ADSCs transplantation in mice with POI. a Changes in serum E2 levels. b Changes in serum FSH levels. c Ovarian histological changes were analyzed using H&E staining. Scale bar: 100 μm. Yellow arrows indicate PrFs located in the ovarian cortex. d The number of follicles at different stages was counted and compared in the control, PBS, ADSCs, and 5 μM MLT-ADSCs groups. PrF, primordial follicle; PF, primary follicle; SF, secondary follicle; AF, antral follicle; E2, estradiol; and FSH, follicle-stimulating hormone. (ns = not significant, *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001)

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Stem Cell Research & Therapy

ISSN: 1757-6512