Fig. 2

BMSCs alleviate hepatic fibrosis in a rat model. The concentration of HA (A), HYP (B) in the liver tissues. The concentration of ALT (C), AST (D), TBIL (E), and ALB (F) in the serum of hepatic fibrosis rats treated with PBS or BMSCs was shown. G H&E and Masson’s staining showing liver microstructure of the collagen deposition in liver tissue of BMSC-treated and PBS-control rats. Magnification, 100×. qPCR (H) and IHC (I) showing the relative mRNA abundance and protein level of ECM-related genes in the liver tissue of rats. Magnification, 40× and 200×. J TUNEL and desmin colocalization staining showing apoptosis of desmin-positive cells in liver tissue after BMSC treatment. Magnification, 400×, scale bar = 50 μm