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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Correction: Overexpressing TGF-β1 in mesenchymal stem cells attenuates organ dysfunction during CLP-induced septic mice by reducing macrophage-driven

Fig. 3

Effect of MSC-TGF-β1 on inflammatory cytokines in the plasma and macrophages in tissue. a, b, c: The levels of IL-6, IL-1β, and IL-10 in the plasma were tested by ELISA (n = 3, *p < 0.05 vs. the sham group; #p < 0.05 vs. the CLP group; &p < 0.05 vs. the MSC-NC group). d, e, f: The levels of macrophages in lung, liver and spleen tissue were assayed by immumohistochemical staining. (n = 3, *p < 0.05 vs. the sham group; #p < 0.05 vs. the CLP group; &p < 0.05 vs. the MSC-NC group). Scale bar = 100 μm. Abbreviations: CLP: cecal ligation and puncture; MSCs, mesenchymal stem cells; MSC-NC: mesenchymal stem cell carrying GFP; MSC-TGF-β1: TGF-β1 overexpressing MSC

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Stem Cell Research & Therapy

ISSN: 1757-6512