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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Downregulation of DNA methyltransferase-3a ameliorates the osteogenic differentiation ability of adipose-derived stem cells in diabetic osteoporosis via Wnt/β-catenin signaling pathway

Fig. 3

Increase of the DNA methylation level in DOP-ASCs. A, B: RT-PCR and western blot analyses showing that the expression of Dnmt1, Dnmt3a, and Dnmt3b in DOP-ASCs was increased compared with that in control ASCs. C, D: Immunofluorescence showing increases in 5-MC, DNMT1, DNMT3a, and DNMT3b after 4 days of osteoinduction. Data represent the mean ± SD of at least three independent experiments, *P < 0.05, **P < 0.01

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