Fig. 2

BMSCs injection improved erectile function and prevented fibrosis in a rat model of PD. A Erectile function measurement in each group at various voltages during cavernous nerve electrostimulation. ICP/MAP: intracavernous pressure (ICP) normalized over mean arterial pressure (MAP); ∆ ICP: ICP change from baseline to peak ICP. B Histological changes in penile tissue cross sections were observed by H&E. BMSCs (early treatment): BMSCs were treated at the active phase of PD; BMSCs (late treatment): BMSCs were treated at the chronic phase of PD. C Fibrotic changes in penile tissue cross sections were observed by Masson. Collagen fibre area was analysed using ImageJ software (version 6.1, USA). ^**P < 0.01 versus the sham group; ^#P < 0.05, ^##P < 0.01 versus the PD + PBS group; ^{^}P < 0.05, ^{^^}P < 0.01 the versus PD + BMSCs (early treatment) group