Fig. 1

AEC-SC attenuated IMQ-induced psoriasis-like skin lesions. a A schematic illustration of animal experiment design. b Representative phenotypic image of mouse back skin after 6-day IMQ administration and different medium treatment. CON represents normal control mice. c Representative images of H&E staining of the back skin of mice in different groups. Scale bar: 50 μm. d Quantification of the epidermal thickness of mice in different groups. The data are expressed as mean ± SEM. At least six representative sections of the skin of mice were counted. At least three mice were used in each group. **P < 0.01, ***P < 0.001. e Immunostaining of back skin tissue of mice with Ki67 antibody and the representative images are shown. Scale bar: 50 μm. f Qualification of the number of Ki67 positive cells per field of the back skin of mice in different groups. g The relative mRNA levels of FLG, HENR and IVL in the back skin of mice in different groups. The mRNA levels of genes in CON group were set as 1. Data were collected from at least 3 mice and the data are expressed as the mean ± SEM, *P < 0.05, **P < 0.01, ***P < 0.001