Skip to main content
Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Circular RNA BIRC6 depletion promotes osteogenic differentiation of periodontal ligament stem cells via the miR-543/PTEN/PI3K/AKT/mTOR signaling pathway in the inflammatory microenvironment

Fig. 7

MiR-543 mimic rescued PDLSC osteogenic differentiation capacity inhibited by circBIRC6 overexpression under the inflammatory microenvironment. A The ALP staining intensity of PDLSCs with indicated treatments. B The mineralized nodules formation capacity of PDLSCs with indicated modifications was examined with ARS staining. C–E qRT-PCR, WB and immunofluorescence staining were performed to evaluated the alterations in osteogenic differentiation makers in PDLSCs with indicated treatments. Scale bar: 20 μm. Data are presented as the mean ± SD (***P < 0.001)

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512