Skip to main content
Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Infusion of two-dose mesenchymal stem cells is more effective than a single dose in a dilated cardiomyopathy rat model by upregulating indoleamine 2,3-dioxygenase expression

Fig. 7

Treatment with IDO-OE hUCMSC inhibits cardiomyocyte apoptosis in DCM rats. A, B TUNEL (red) and anti-TnT (green) co-staining of heart samples and quantitative analysis of the percentages of apoptotic cardiomyocytes in rats at 8 weeks post-induction, scale bar = 50 μm. C, D Western blot and quantitative analysis of the relative levels of BAX and BcL-2 expression in heart tissues of rats. E, F Western blot analysis of the relative levels of IDO, BAX and BcL-2 expression in cardiomyocytes. Data are mean ± SEM of each group (N = 3–5 rats per group) from two separate experiments. *P < 0.05, **P < 0.001, ***P < 0.001 by one-way ANOVA

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512