Table 1 Baseline clinical characteristics of enrolled patients

Age (years)

13 (7–18)

Gender

10 F: 1 M

Disease duration (months)

32 (7–142)

Proteinuria (uPr/uCr mg/mg)

8.13 (2.43–18.26)

Previous lines of therapy

3 (2–6)

eGFR (mL/min/1.73m²)

113.9 (55.7–139)

Serum creatinine (mg/dL)

0.74 (0.28–1.79)

Serum total protein (g/dL)

4.5 (3.6–5.6)

Serum albumin (g/dL)

2.6 (1.5–3.5)

Total cholesterol (mg/dL)

347 (167–684)

Triglycerides (mg/dL)

232 (110–552)

Serum cytokine level (pg/mL)

 IFN-gamma

0.065 (0.03–2.612)

 IL-6

1.304 (0.699–5.537)

 IL-8

17.8 (13.9–50.2)

 IL-10

1.1 (0.5–2.2)

 TNF-alfa

6.485 (2.765–13.159)

 IL-1 beta

0.121 (0.091–0.574)