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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Stable expression of a truncated TLX variant drives differentiation of induced pluripotent stem cells into self-renewing neural stem cells for production of extracellular vesicles

Fig. 2

NGD-I medium-induced rapid differentiation of iPSCsTLX−FL/TP into neuroepithelial cells. A Morphology of iPSCsTLX−FL/TP cultured in SMAD inhibitor-containing medium or NGD-I medium. Cells cultured in NGD-I showed the emergence of the neural rosette. B Schematic representation of differentiation timeline of iPSCsWT or iPSCsTLX−FL/TP lines in SMAD inhibitor-containing medium or NGD-I medium, and the expression of Nestin, Sox2, Vimentin and Musashi-1 in iPSCsTLX−FL/TP cultured in NGD-I on Day 3 and Day 6, and at passage 2. C Immunofluorescence (IF) staining of iNSCsTLX−TP

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Stem Cell Research & Therapy

ISSN: 1757-6512