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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Stable expression of a truncated TLX variant drives differentiation of induced pluripotent stem cells into self-renewing neural stem cells for production of extracellular vesicles

Fig. 5

Neuronal differentiation of iNSCsTLX−TP. A Morphological, flow cytometric and IF staining analyses at different stages of differentiation of iNSCsTLX−TP into motor neurons. B Electrophysiological signals, such as Na+ and K+ channel currents, evoked the action potential of cells on day 20. C Morphological and IF staining at different stages of differentiation iNSCsTLX−TP into DAPs. D Electrophysiological signals, such as Na+ and K+ channel currents, evoked the action potential of DAP cells on day 22. MNP: motor neuron progenitor; PMN: postmitotic motor neuron; mMN: mature motor neuron; mDAP: midbrain dopaminergic progenitor; mDAN: midbrain dopaminergic neuron

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Stem Cell Research & Therapy

ISSN: 1757-6512