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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Stable expression of a truncated TLX variant drives differentiation of induced pluripotent stem cells into self-renewing neural stem cells for production of extracellular vesicles

Fig. 8

A Heatmap of pathway enrichment analysis, including the top 40 most abundant miRNAs found in an iNSC-EVs (P20-P25) batch. B Inflammation-related gene (IL-1α, IL-1β and TNF-α) expressions in RPG cells after treating with LPS or LPS plus different concentrations iNSC-EVs for 24 h. C Cellular apoptosis analysis of RPN cells after culturing with RPG supernatant for 24 h by flow cytometry. The data are representative of three independent experiments and expressed as the means ± SD, *p < 0.05, ****p < 0.0001, n. s. means no significant difference

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Stem Cell Research & Therapy

ISSN: 1757-6512