Skip to main content
Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: ADSCs stimulated by VEGF-C alleviate intestinal inflammation via dual mechanisms of enhancing lymphatic drainage by a VEGF-C/VEGFR-3-dependent mechanism and inhibiting the NF-κB pathway by the secretome

Fig. 4

The therapeutic effects of VEGF-C-stimulated ADSCs on TNBS-induced colitis. a Survival rate. N = 9 mice per group. b Colitis score. c DAI based on body weight changes, stool traits, and haematochezia. d Weight changes. e Representative images of colon length per group. f Comparison of colon length. g Representative images of colon macroscopic damage per group. h Representative images of mucosal lesions per group. i Macroscopic damage score. j Representative images of representative H&E staining images per group. Scale bar 100 μm; ×200, magnifications. k Histological score. l Representative Masson’s trichrome-stained image per group. Scale bar 100 μm; ×200, magnifications. m Collagen deposition was quantified as a ratio of the positive area to the total area of colon tissues. (N ≥ 5, *P < 0.05, **P < 0.01)

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512