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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Knockdown of FOXA1 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the ERK1/2 signalling pathway

Fig. 7

A sheet of mBMSCs with FOXA1 knockdown accelerated bone healing in a mouse model of femoral defects. A Microcomputed tomography analysis for bone healing. The sheet with FOXA1 knockdown increased the BV, BV/TV and Tb.Th and decreased the Tb.Sp (n = 5). B Histological analysis for bone healing. Hematoxylin and Eosin (H&E) staining, Masson’s Trichrome staining and Safranin O/Fast Green staining, Scale bars = 500 μm. White arrow: the defect area. All data are means ± SDs. *p < 0.05, **p < 0.01, and ***p < 0.001 versus the control group

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Stem Cell Research & Therapy

ISSN: 1757-6512