Time-regulated transcripts with the potential to modulate human pluripotent stem cell-derived cardiomyocyte differentiation

Table 3 Validated targets of hsa-miR-124-3p associated with cardiac development and maturation aspects

Gene ontology term	Gene symbol	Maturation aspects	Symbol	Channels	Symbol
Atrial cardiac muscle cell development	FHL2	Cardiac specification	MEF2C	Sodium channels	SCN3B
Atrioventricular node cell development	MAML1		MESP1		SCN9A
	BMPR1A		MIXL1	Calcium channels	ATP2A1
Cardiac muscle cell development	MTOR	Adult cardiac related	MYL7		ATP1A3
	SGCB		TNNI3		CACNA2D1
	ZMPSTE24		TNNC1		CALM1
	VEGFA		NPPB		CLCN2
					RYR2
	ASB2	Cardiac subtype fate	NR2F2
	CXADR		SLN		SNTA1
	HNRNPU		GJA1	Potassium channels	KCNA5
	PLEC		PIAS3		KCNC4
Cell growth involved in cardiac muscle cell development	PDLIM5
Cell growth involved in cardiac muscle cell development	AKAP13	Cell connection	DSG2		KCNE3
Sinoatrial node cell development	TBX3				KCNE4
	BVES	T-tubule formation	BIN1
					KCNK1
Ventricular cardiac muscle cell development	LMNA
					KCNK5
	ATG5	Metabolism	TFAM
				RYR2 modulatory proteins	CAMK2D
			ITPR3		CALM1
	FHL2
					CALM3
					FKBP1A
			ANK2		ASPH
	CDK1
					CASQ2
					CAMK2D

ISSN: 1757-6512