Table 1 The comparison of characteristics among embryonic stem cells, somatic-iPSCs, cancer-iPSCs, and cancer cells
From: Cancer cells as a new source of induced pluripotent stem cells
Characteristics | PSCS | |||
|---|---|---|---|---|
Embryonic stem cells | Somatic-iPSCs | Cancer-iPSCs | Cancer cells | |
Pluripotency | + | + | + | − |
Proliferation | + | + | + | + |
Self-renewal | + | + | + | − |
Immortality | + | + | + | + |
Expression of ECS marker genes | + | + | + | − |
Availability | − | + |  ±  |  ±  |
Ethical concerns related to isolation | + | − | − | − |
Telomere elongation | + | + | + | + |
Teratoma formation | + | + | + | − |
Tumor formation | + | + | + | + |