Fig. 5
From: The role of DNA demethylation in liver to pancreas transdifferentiation
DNA demethylation agent 5-AZA promotes pTF-induced TD: liver cells were treated by increasing amounts of 5-AZA (0–4 µM), 48 h before induction of trans-differentiation by ectopic pTF expression. The expression levels of pancreatic specific transcription factors (A) and pancreatic specific genes (B) was measured 6 days post TD induction by RT-qPCR. Results are presented as average ± SD, n = 6 different donors, *p < 0.01, **p < 0.05