Fig. 5
NAC-treated rDFSCs promoted tooth extraction socket bone formation. A The right maxillary first molars were extracted and filled with gelatin sponges carried vehicle (15 μL, PBS), NAC (15 μL, 5 mM), rDFSCs (15 μL, 1 × 106 cells) or NAC-treated rDFSCs (15 μL, 5 mM NAC, 1 × 106 cells), then sealed with cyanoacrylate glue. B Representative photomicrographs of HE-stained tooth extraction sockets. Original magnification: 4 × . C Representative photomicrographs of masson trichrome-stained tooth extraction sockets. Original magnification: 4 × . D Three-dimensional reconstruction and section images of tooth extraction sockets using micro-CT. Micro-CT assessment of BV/TV (E), BMD (F), Tb.Th (G), Tb.N (H), Tb.Sp (I). Statistically significant differences between groups were determined by P < 0.05 (*), P < 0.01 (**), P < 0.001 (***), P < 0.0001 (****)