Fig. 1

Plasma Hp dose-dependent increases in mice after exposure to different doses of TBI. A Survival rate, and Lymphocyte count. The P value of survival rate determined by log-rank (Mantel-Cox) test. Data are mean ± SD of n = 8 mice per group, statistical significance by Student’s t-test. Hp haptoglobin, TBI total body irradiation. ****, P < 0.0001. ***, P < 0.001. *, P < 0.05. B Fold change in Hp from plasma of animals in A at different time after TBI. Data are mean ± SD of n = 8 mice per group, statistical significance by Student’s t-test. Hp haptoglobin, TBI total body irradiation. Additional file 1: Table S1 shows fold change and P value of the data. C The correlation between Hp concentration and radiation dose at 3 h, 6 h, 12 h, 1 day, 2 days and 3 days after irradiation